A scoring system to detect fixed airflow limitation in smokers from simple easy-to-use parameters
Por:
Román-Conejos E, Palazón-Bru A, Folgado-de la Rosa DM, Sánchez-Molla M, Rizo-Baeza MM, Gil-Guillén VF and Cortés-Castell E
Publicada:
6 sep 2018
Ahead of Print:
6 sep 2018
Categoría:
Multidisciplinary
Resumen:
No validated screening method currently exists for Chronic Obstructive Pulmonary Disease (COPD) in smokers. Therefore, we constructed a predictive model with simple parameters that can be applied for COPD screening to detect fixed airflow limitation. This observational cross-sectional study included a random sample of 222 smokers with no previous diagnosis of COPD undertaken in a Spanish region in 2014-2016. The main variable was fixed airflow limitation by spirometry. The secondary variables (COPD factors) were: age, gender, smoking (pack-years and Fagerstrom test), body mass index, educational level, respiratory symptoms and exacerbations. A points system was developed to predict fixed airflow limitation based on secondary variables. The model was validated internally through bootstrapping, determining discrimination and calibration. The system was then integrated into a mobile application for Android. Fifty-seven patients (25.7%) presented fixed airflow limitation. The points system included as predictors: age, pack-years, Fagerstrom test and presence of respiratory symptoms. Internal validation of the system was very satisfactory, both in discrimination and calibration. In conclusion, a points system has been constructed to predict fixed airflow limitation in smokers with no previous COPD. This system can be integrated as a screening tool, though it should be externally validated in other geographical regions.
Filiaciones:
Román-Conejos E:
Raval Health Centre, Generalitat Valenciana, Elche, Alicante, Spain
:
Department of Clinical Medicine, Miguel Hernández University, San Juan de Alicante, Alicante, Spain.
Folgado-de la Rosa DM:
Department of Clinical Medicine, Miguel Hernández University, San Juan de Alicante, Alicante, Spain
Sánchez-Molla M:
Department of Medical Management, University General Hospital of Elche, Elche, Alicante, Spain
Rizo-Baeza MM:
Department of Nursing, University of Alicante, San Vicente del Raspeig, Alicante, Spain
:
Department of Clinical Medicine, Miguel Hernández University, San Juan de Alicante, Alicante, Spain
Cortés-Castell E:
Department of Pharmacology, Pediatrics and Organic Chemistry, Miguel Hernández University, San Juan de Alicante, Alicante, Spain
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