Multicentric study on total pancreatectomies
Por:
Ramia, J, Martin-Perez, E, Poves, I, Fabregat-Prous, J, Olea, J, Sanchez-Bueno, F, Botello-Martinez, F, Briceno, J, Miyar-de Leon, A, Serradilla, M, Moya-Herraiz, A, Secanella, L, Bueno, F, Serrablo, A, Fabrega, J, Cabus, S, Bravo, M, Padillo, J, Blanco, L, Balcells, J, Cugat, E, Domingo, M, Bellvis, L, Diaz, M, Santoyo, J, Sanchez, B, Georgiev, T, Villegas, T, Pacho, S, Valladares, L, Rebollar, J, Munoz, M, Dominguez, E, Falgueras, L, Artigas, V, Sabater, L, Gil, A, de Llama, J, Manzanet, G, Pino, J, Sanjuan, J, Lluis, F, Ausania, F, Zuloaga, M, Escartin, J, Salas, M, Domingo, C, de Rojas, E, Mateos, J, Cebrian, J, Cabrera, B, Valverde, D, Sanjuanbenito, A, Belmonte, I, Bejarano, N, Borobia, F, Guinea, P, Marcano, A, Arana, F, Varo, E, Esteban, R, Blas, J, Navalon, J, Martinez, C, Collado, E, Duran, A, Vicens, J, Romero, J, Badia, J, Sanchez, R, Ibanez, R, Pardo, F, von Hunefeld, C, Pereira, F, Molina, F, Prieto, I, Poza, A, Gilsanz, C, Albert, J, Morcillo, M, Cortijo, S, Fernandez, J, Baquedano, J, Castell, J, Aguilo, J and Bernal, J
Publicada:
1 ago 2019
Resumen:
Introduction: Total pancreatectomy (TP) is an uncommon operation, with indications that have not been clearly defined and non-standardized postoperative results. We present a national multicentric study on TP and a comparison with the existing literature
Methods: A prospective observational study using data from the national registry of patients after pancreaticoduodenectomy and TP performed for any indication during the study period: January 1 to December 31, 2015
Results: 1016 patients were included from 73 hospitals, 112 of whom had undergone TP. The percentage of TP from the total number of cases was 11%. The mean age was 63.5 years, and 57.2% were males. The most frequently suspected radiological diagnosis was pancreatic cancer (58/112 cases). The most common TP technique was "mesentery artery first" (43/112 cases). Venous resections were performed in 23 patients (20.5%). The percentage of postoperative complications within 90 days was 50%, but major complications (>IIIA) were only 20.7%. The overall 90-day mortality was 8% (9 patients). The average stay was 20.7 days. The 3 most frequent definitive histological diagnoses were: adenocarcinoma of the pancreas, intraductal papillary mucinous neoplasm and chronic pancreatitis. The R0 rate was 67.8%.
Conclusions: This study shows that the morbidity and mortality results of TP in Spain are similar or superior to previous publications. More precise TP studies are necessary, focused on specific complications such as endocrine insufficiency. (C) 2019 AEC. Published by Elsevier Espana, S.L.U. All rights reserved.
Filiaciones:
Ramia, J:
Hosp Univ Guadalajara, Serv Cirugia, Guadalajara, Spain
Martin-Perez, E:
Hosp La Princesa, Serv Cirugia, Madrid, Spain
Hosp La Princesa, Madrid, Spain
Poves, I:
Hosp del Mar, Serv Cirugia, Barcelona, Spain
Hosp del Mar, Barcelona, Spain
Fabregat-Prous, J:
Hosp Univ Bellvitge, Serv Cirugia, Barcelona, Spain
Hosp Univ Bellvitge, Barcelona, Spain
Olea, J:
Hosp Univ Insular Gran Canaria, Serv Cirugia, Las Palmas Gran Canaria, Las Palmas, Spain
Hosp Univ Insular Gran Canaria, Las Palmas Gran Canaria, Spain
Sanchez-Bueno, F:
Hosp Univ Virgen de la Arrixaca, Serv Cirugia, Murcia, Spain
Hosp Clin Univ Virgen de la Arrixaca, Murcia, Spain
Botello-Martinez, F:
Hosp Univ Infanta Cristina, Serv Cirugia, Badajoz, Spain
Hosp Univ Infanta Cristina, Badajoz, Spain
Briceno, J:
Hosp Univ Reina Sofia, Serv Cirugia, Cordoba, Spain
Hosp Reina Sofia, Cordoba, Spain
Miyar-de Leon, A:
Hosp Univ Cent Asturias, Serv Cirugia, Oviedo, Asturias, Spain
Hosp Univ Cent Asturias, Oviedo, Spain
Serradilla, M:
Hosp Univ Miguel Servet, Serv Cirugia, Zaragoza, Spain
Hosp Univ Miguel Servet, Zaragoza, Spain
Moya-Herraiz, A:
Hosp Gen Castello, Serv Cirugia, Castellon de La Plana, Castellon, Spain
Secanella, L:
Hosp Univ Bellvitge, Barcelona, Spain
Bueno, F:
Hosp Univ Virgen de la Arrixaca, Serv Cirugia, Murcia, Spain
Hosp Clin Univ Virgen de la Arrixaca, Murcia, Spain
Serrablo, A:
Hosp Univ Miguel Servet, Zaragoza, Spain
Fabrega, J:
Hosp Clin Barcelona, Barcelona, Spain
Cabus, S:
Hosp Clin Barcelona, Barcelona, Spain
Bravo, M:
Hosp Univ Virgen del Rocio, Seville, Spain
Padillo, J:
Hosp Univ Virgen del Rocio, Seville, Spain
Blanco, L:
Hosp Univ Vall dHebron, Barcelona, Spain
Balcells, J:
Hosp Univ Vall dHebron, Barcelona, Spain
Cugat, E:
Hosp Mutua Terrassa, Barcelona, Spain
Domingo, M:
Hosp Mutua Terrassa, Barcelona, Spain
Bellvis, L:
Hosp Clin Univ Salamanca, Salamanca, Spain
Diaz, M:
Hosp Gen Univ Gregorio Maranon, Madrid, Spain
Santoyo, J:
Hosp Carlos Haya, Malaga, Spain
Sanchez, B:
Hosp Carlos Haya, Malaga, Spain
Georgiev, T:
Hosp Fdn Jimenez Diaz, Hosp Univ Rey Juan Carlos, Hosp Univ Infanta Elena, Grp ICD Salud, Madrid, Spain
Villegas, T:
Hosp Virgen de las Nieves, Granada, Spain
Pacho, S:
Complejo Asistencial Univ Leon, Leon, Spain
Valladares, L:
Hosp Univ Clin San Carlos, Madrid, Spain
Rebollar, J:
Hosp Univ Alava, Vitoria, Alava, Spain
Munoz, M:
Hosp Virgen de la Victoria, Malaga, Spain
Dominguez, E:
Complexo Hosp Univ Pontevedra, Pontevedra, Spain
Falgueras, L:
Hosp Josep Trueta, Girona, Spain
Artigas, V:
Hosp Santa Creu & Sant Pau, Barcelona, Spain
Sabater, L:
Hosp Clin Univ, Valencia, Spain
Gil, A:
Hosp Clin Lozano Blesa, Zaragoza, Spain
de Llama, J:
Hosp Gen Univ Albacete, Albacete, Spain
Manzanet, G:
Hosp Univ La Plana, Castellon de La Plana, Spain
Pino, J:
Hosp Son Espases, Palma De Mallorca, Spain
Sanjuan, J:
Hosp Univ Marques de Valdecilla, Santander, Spain
:
Hosp Gen Alicante, Alicante, Spain
Ausania, F:
Complexo Hosp Univ Vigo, Vigo, Pontevedra, Spain
Zuloaga, M:
Hosp Univ Donostia, San Sebastian, Spain
Escartin, J:
Hosp Arnau Vilanova, Lleida, Spain
Salas, M:
Hosp Badalona Germans Trias & Pujol, Barcelona, Spain
Domingo, C:
Hosp Doctor Peset, Valencia, Spain
de Rojas, E:
Consorci Hosp Gen Univ, Valencia, Spain
Mateos, J:
Hosp Gen Univ Elda, Alicante, Spain
Cebrian, J:
Hosp Univ Fdn Alcorcon, Madrid, Spain
Cabrera, B:
Hosp Univ San Cecilio, Granada, Spain
Valverde, D:
Hosp Gen Univ Ciudad Real, Ciudad Real, Spain
Sanjuanbenito, A:
Hosp Univ Ramon y Cajal, Madrid, Spain
Belmonte, I:
Hosp Basurto, Bilbao, Spain
Bejarano, N:
Hosp Parc Tauli, Barcelona, Spain
Borobia, F:
Hosp Parc Tauli, Barcelona, Spain
Guinea, P:
Hosp Virgen Salud, Toledo, Spain
Marcano, A:
Hosp Univ Guadalajara, Guadalajara, Spain
Arana, F:
Hosp Arnau Vilanova, Valencia, Spain
Varo, E:
Complexo Hosp Univ Santiago, La Coruna, Spain
Esteban, R:
IVO, Valencia, Spain
Blas, J:
Hosp Royo Vilanova, Zaragoza, Spain
Navalon, J:
Hosp Univ Getafe, Madrid, Spain
Martinez, C:
Hosp Sagunto, Valencia, Spain
Collado, E:
Complejo Hosp Jaen, Jaen, Spain
Duran, A:
Hosp Univ Puerta Mar, Cadiz, Spain
Vicens, J:
Hosp Son Llatzer, Palma De Mallorca, Spain
Romero, J:
Hosp Son Llatzer, Palma De Mallorca, Spain
Badia, J:
Hosp Granollers, Barcelona, Spain
Sanchez, R:
Quirdrg Cirujanos Asociados, Barcelona, Spain
Ibanez, R:
Hosp Virgen Salud, Cuenca, Spain
Pardo, F:
Clin Univ Navarra, Navarra, Spain
von Hunefeld, C:
Complejo Asistencial Hosp Nuestra Senora Sonsole, Avila, Spain
Pereira, F:
Hosp Univ Fuenlabrada, Madrid, Spain
Molina, F:
Hosp Jerez Frontera, Cadiz, Spain
Prieto, I:
Hosp Univ Infanta Cristina, Madrid, Spain
Poza, A:
Hosp Univ Sureste, Madrid, Spain
Gilsanz, C:
Hosp Univ Sureste, Madrid, Spain
Albert, J:
Hosp Manises, Valencia, Spain
Morcillo, M:
Hosp Orihuela, Alicante, Spain
Cortijo, S:
Hosp Gen Nuestra Senora Prado, Toledo, Spain
Fernandez, J:
Hosp Univ Principe Asturias, Madrid, Spain
Baquedano, J:
Hosp Cent Def, Madrid, Spain
Castell, J:
Hosp Univ La Paz, Madrid, Spain
Aguilo, J:
Hosp Lluis Alcanis, Valencia, Spain
Bernal, J:
Hosp Requena, Valencia, Spain
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