Achievement of metabolic control among children and adolescents with type 1 diabetes in Spain.
Por:
Rica I, Mingorance A, Gómez-Gila AL, Clemente M, González I, Caimari M, García-Cuartero B and Barrio R
Publicada:
1 jul 2017
Ahead of Print:
18 abr 2017
Resumen:
AIMS: To assess metabolic control in a paediatric T1D population in Spain and analyse the rate of severe acute decompensations and chronic complications. METHODS: Data from patients treated at eight paediatric diabetes units with experienced diabetes teams between June and December 2014 were analysed in an observational prospective study. Variables included: age, sex, diabetes duration, number of follow-up visits/year, anthropometrical data, insulin treatment modalities, mean annual HbA1c and the prevalence of acute and chronic complications. SPSS statistics 21.0 was used. RESULTS: A total of 853 patients (49.7% female) with a mean age of 12.1 ± 3.7 years were included. Anthropometric data were normal. Mean diabetes duration was 8 ± 3.4 years. Mean outpatient follow-up was 4.7 ± 0.04 visits/year. Twenty-five per cent were on continuous subcutaneous insulin infusion (CSII). Mean HbA1c was 7.3 ± 1% (56 ± 8 mmol/mol) and 66.6% had HbA1c < 7.5% (58 mmol/mol). HbA1c value correlated negatively with age at onset and positively with years of diabetes, number of visits/year and current age (F = 7.06; p = 0.01). Patients on CSII (n = 213) were younger, attended the outpatient clinic more frequently, were diagnosed earlier, had better metabolic control and had presented more severe hypoglycaemic episodes the previous year. The rate of severe decompensation (episodes/100 patients/year) was ketoacidosis 1.5 and severe hypoglycaemia 4.5. The prevalence of chronic complications was very low. CONCLUSIONS: Our data describe the good compliance of paediatric T1D patients treated at eight paediatric units in Spain following international standards of metabolic control.
Filiaciones:
Rica I:
Paediatric Endocrinology, Hospital Universitario de Cruces, CIBERDEM, CIBERER, BIOCRUCES, Plaza Cruces s/n, 48903, Barakaldo, Bizkaia, Spain
:
Paediatric Endocrinology, Hospital General Universitario de Alicante, Pintor Baeza 11, 03010, Alicante, Spain
Gómez-Gila AL:
Paediatric Endocrinology Unit. Paediatric Service, Hospital Infantil, HHUU Virgen Rocío, Avda Marques Luca de Tena s/n, Seville, Spain
Clemente M:
Paediatric Endocrinology Unit, Paediatric Service, Growth and Development Research Unit, Vall d'Hebron Research Institute (VHIR), Hospital Vall d'Hebron, CIBERER, Instituto de Salud Carlos III, Ps. Vall d´Hebron 119-129, 08035, Barcelona, Spain.
González I:
Paediatric Endocrinology, Hospital Infantil La Paz, Pº Castellana 261, 28046, Madrid, Spain
Caimari M:
Paediatric Endocrinology, Hospital Universitario Son Espases, Carretera Valldemosa, 79, 07010, Palma de Mallorca, Spain
García-Cuartero B:
Paediatric Endocrinology Unit, Severo Ochoa University Hospital, 28911, Leganés, Madrid, Spain
Barrio R:
Paediatric Endocrinology and Diabetes Unit, Ramón y Cajal University Hospital, Cta. Colmenar Viejo 9, 100, 28034, Madrid, Spain
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