Schistosomiasis in European Travelers and Migrants: Analysis of 14 Years TropNet Surveillance Data.
Por:
Lingscheid T, Kurth F, Clerinx J, Marocco S, Trevino B, Schunk M, Muñoz J, Gjørup IE, Jelinek T, Develoux M, Fry G, Jänisch T, Schmid ML, Bouchaud O, Puente S, Zammarchi L, Mørch K, Björkman A, Siikamäki H, Neumayr A, Nielsen H, Hellgren U, Paul M, Calleri G, Kosina P, Myrvang B, Ramos JM, Just-Nübling G, Beltrame A, Saraiva da Cunha J, Kern P, Rochat L, Stich A, Pongratz P, Grobusch MP, Suttorp N, Witzenrath M, Hatz C, Zoller T and TropNet Schistosomiasis Investigator Group
Publicada:
1 ago 2017
Ahead of Print:
19 jul 2017
Resumen:
Schistosomiasis remains one of the most prevalent parasitic diseases worldwide and the infection is frequently found in travelers and migrants. The European Network for Tropical Medicine and Travel Health conducted a sentinel surveillance study on imported schistosomiasis between 1997 and 2010. This report summarizes epidemiological and clinical data from 1,465 cases of imported schistosomiasis. Direct pathogen detection and serology were the main diagnostic tools applied. Of these, 486 (33%) cases were identified among European travelers, 231 (16%) among long-term expatriates, and 748 (51%) among non-European immigrants. Overall, only 18.6% of travelers had received pretravel advice; 95% of infections were acquired in the African region. On species level, Schistosoma mansoni was identified in 570 (39%) and Schistosoma haematobium in 318 (22%) cases; 57.5% of patients were symptomatic. Acute symptoms were reported in 27% of patients leading to earlier presentation within 3 months. Praziquantel was used in all patients to treat schistosomiasis. Many infections were detected in asymptomatic patients. In 47.4% of asymptomatic patients infection was detected by microscopy and in 39% by serology or antigen testing. Schistosomiasis remains a frequent infection in travelers and migrants to Europe. Travelers should be made aware of the risk of schistosomiasis infection when traveling to sub-Saharan Africa. Posttravel consultations particularly for returning expatriates are useful given the high potential for detecting asymptomatic infections.
Filiaciones:
Lingscheid T:
Medizinische Klinik mit Schwerpunkt Infektiologie und Pneumologie, Charité Universitätsmedizin Berlin, Berlin, Germany
Kurth F:
Medizinische Klinik mit Schwerpunkt Infektiologie und Pneumologie, Charité Universitätsmedizin Berlin, Berlin, Germany
Clerinx J:
Institute of Tropical Medicine, Antwerp, Belgium
Marocco S:
Centro per le Malattie Tropicali, Ospedale S. Cuore, Negrar, Verona, Italy
Trevino B:
Tropical Medicine and International Health Unit, Hospital Vall d'Hebron Drassanes, PROSICS Barcelona, Barcelona, Spain
Schunk M:
Division of Infectious Diseases and Tropical Medicine, Medical Centre of the Ludwig-Maximilians-University (LMU), Munich, Germany
Muñoz J:
ISGlobal, Barcelona Centre for International Health Research (CRESIB), Hospital Clínic-Universitat de Barcelona, Barcelona, Spain
Gjørup IE:
Infectious Diseases Unit, Herlev University Hospital, Copenhagen, Denmark
Jelinek T:
Berlin Centre for Travel and Tropical Medicine, Berlin, Germany
Develoux M:
Service de Parasitologie, Hôpital Saint-Antoine, Paris, France
Fry G:
Tropical Medical Bureau, Dublin, Ireland
Jänisch T:
Department of Infectious Diseases, University Hospital Heideberg, Heidelberg, Germany
Schmid ML:
Department of Infection and Tropical Medicine, Royal Victoria Infirmary, Newcastle upon Tyne, United Kingdom
Bouchaud O:
Consultation de médecine tropicale, Hôpital Avicenne, Bobigny, France
Puente S:
Hospital Carlos III, Madrid, Spain
Zammarchi L:
Infectious Diseases Unit, Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy
Mørch K:
Department of Medicine, National Centre for Tropical Infectious Diseases, Haukeland University Hospital, Bergen, Norway
Björkman A:
Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden
Siikamäki H:
Inflammation Centre, Clinic of Infectious Diseases, University of Helsinki and Helsinki University Hospital, Helsinki, Finland
Neumayr A:
University of Basel, Basel, Switzerland
Swiss Tropical and Public Health Institute, Basel, Switzerland
Nielsen H:
Department of Infectious Diseases, Aalborg University Hospital, Aalborg, Denmark
Hellgren U:
Unit of Infectious Diseases, Department of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden
Paul M:
Department and Clinic of Tropical and Parasitic Diseases, Karol Marcinkowski University of Medical Sciences, Poznan, Poland
Calleri G:
Travel Medicine Unit, Department of Infectious Diseases, Amedeo di Savoia Hospital-ASLTO2, Turin, Italy
Kosina P:
Department of Infectious Diseases, University Hospital, Hradec Králové, Czech Republic
Myrvang B:
Oslo University Hospital, Ullevål, Norway
:
Infectious Diseases Unit, Hospital General Universitario de Elche, Alicante, Spain
Just-Nübling G:
Department of Internal Medicine II, Section Infectious Diseases and Tropical Medicine, University Hospital Frankfurt, Main, Germany
Beltrame A:
Clinic of Infectious Diseases, University of Udine, Udine, Italy
Centro per le Malattie Tropicali, Ospedale S. Cuore, Negrar, Verona, Italy
Saraiva da Cunha J:
Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal
Kern P:
Department of Internal Medicine III, Comprehensive Infectious Diseases Center, Ulm University Hospital, Ulm, Germany
Rochat L:
Department of Ambulatory Care and Community Medicine, Travel Clinic, University Hospital, Lausanne, Switzerland
Stich A:
Abteilung Tropenmedizin, Missionsärztliche Klinik, Würzburg, Germany
Pongratz P:
Division of Tropical Medicine and Infectious Diseases, Rostock University Medical Center, Germany
Grobusch MP:
Center of Tropical Medicine and Travel Medicine, Academic Medical Center, University of Amsterdam, The Netherlands
Suttorp N:
Medizinische Klinik mit Schwerpunkt Infektiologie und Pneumologie, Charité Universitätsmedizin Berlin, Berlin, Germany
Witzenrath M:
Medizinische Klinik mit Schwerpunkt Infektiologie und Pneumologie, Charité Universitätsmedizin Berlin, Berlin, Germany
Hatz C:
Epidemiology, Biostatistics and Prevention Institute, University of Zurich, Zurich, Switzerland
University of Basel, Basel, Switzerland
Swiss Tropical and Public Health Institute, Basel, Switzerland
Zoller T:
University of Basel, Basel, Switzerland
Swiss Tropical and Public Health Institute, Basel, Switzerland
Medizinische Klinik mit Schwerpunkt Infektiologie und Pneumologie, Charité Universitätsmedizin Berlin, Berlin, Germany
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