Hidradenitis Suppurativa is Associated with Non-alcoholic Fatty Liver Disease: A Cross-sectional Study
Por:
Gonzalez-Villanueva, I, De Gracia, C, Planells, M, Poveda, I, Alvarez, P, Schneller-Pavalescu, L, Betlloch, I, Jemec, G, Ramos, J and Pascual, J
Publicada:
1 ago 2020
Resumen:
Non-alcoholic fatty liver disease (NAFLD) is currently the most common cause of end-stage liver disease. The aim of this controlled cross-sectional study was to assess the association between NAFLD and hidradenitis suppurativa. NAFLD was assessed using hepatic ultrasound. A total of 125 patients with hidradenitis suppurativa and 120 patients without hidradenitis suppurativa were recruited, matched for age, sex and body mass index (< 25 or >= 25 kg/m(2)), a risk factor related to NAFLD. Both groups presented similar proportions of overweight or obesity (89.6% vs 90%). Patients with hidradenitis suppurativa presented significantly higher prevalence of NAFLD compared with those with non-hidradenitis suppurativa (57.6% vs 31.7%, p < 0.001). Multivariable analysis confirmed independent association between hidradenitis suppurativa and NAFLD (odds ratio 2.79, 95% confidence interval 1.48-5.25; p = 0.001) besides age, body mass index, hypertension and hypertransaminasaemia. Hidradenitis suppurativa is significantly associated with the development of NALFD regardless of the presence of classic metabolic risk factors.
Filiaciones:
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Univ Gen Hosp, ISABIAL FISABIO Fdn, Alicante Inst Hlth & Biomed Res, Dept Dermatol, C Maestro Alonso S-N, ES-03010 Alicante, Spain
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Univ Gen Hosp, ISABIAL FISABIO Fdn, Alicante Inst Hlth & Biomed Res, Dept Radiol, Alicante, Spain
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Univ Gen Hosp, ISABIAL FISABIO Fdn, Alicante Inst Hlth & Biomed Res, Dept Radiol, Alicante, Spain
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Univ Gen Hosp, ISABIAL FISABIO Fdn, Alicante Inst Hlth & Biomed Res, Dept Dermatol, C Maestro Alonso S-N, ES-03010 Alicante, Spain
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Univ Gen Hosp, ISABIAL FISABIO Fdn, Alicante Inst Hlth & Biomed Res, Dept Dermatol, C Maestro Alonso S-N, ES-03010 Alicante, Spain
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Univ Gen Hosp, ISABIAL FISABIO Fdn, Alicante Inst Hlth & Biomed Res, Dept Dermatol, C Maestro Alonso S-N, ES-03010 Alicante, Spain
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Univ Gen Hosp, ISABIAL FISABIO Fdn, Alicante Inst Hlth & Biomed Res, Dept Dermatol, C Maestro Alonso S-N, ES-03010 Alicante, Spain
Jemec, G:
Univ Copenhagen, Hlth Sci Fac, Zealand Univ Hosp Roskilde, Dept Dermatol, Copenhagen, Denmark
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Univ Gen Hosp, ISABIAL FISABIO Fdn, Alicante Inst Hlth & Biomed Res, Dept Internal Med Alicante, Alicante, Spain
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Univ Gen Hosp, ISABIAL FISABIO Fdn, Alicante Inst Hlth & Biomed Res, Dept Dermatol, C Maestro Alonso S-N, ES-03010 Alicante, Spain
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