Sex differences and HIV status of tuberculosis in adults at a rural hospital in southern Ethiopia: an 18-year retrospective cross-sectional study
Por:
Ramos, J, Comeche, B, Tesfamariam, A, Reyes, F, Tiziano, G, Balcha, S, Edada, T, Biru, D, Perez-Butragueno, M and Gorgolas, M
Publicada:
1 jun 2020
Resumen:
Background. The aim of the study was to compare the epidemiology, clinical characteristics and treatment outcome of tuberculosis (TB), including HIV status, in women and men in southern rural Ethiopia.
Methods. We conducted a register-based retrospective cohort study covering the period from September 1998 to August 2015.
Results. We included records of 2252 registered TB patients: 1080 (48%) women and 1172 (52%) men. Median age was similar for women and men: 27.5 years and 25.0 years, respectively. Median weight in women was 43.0 kg (interquartile range IQR: 38.0, 49.0), significantly lower than in men (50.0 kg, IQR 44.0, 55.0; p = 0.01). Extrapulmonary TB was significantly more common in women than in men (34.1% versus 28.7%; p=0.006). Treatment outcomes were similar in both sexes: in 70.3% of women and 68.9% of men, TB mortality was slightly lower in women than men (4.7% vs. 6.5%; p=0.08). In patients with TB, female sex was independently associated with low weight (adjusted aOR: 0.91; 95% CI 0.90, 0.92), less mortality (aOR: 0.54; 95% CI 0.36, 0.81), and lymph node TB (aOR: 1.57; 95% CI 1.13, 2.19)
Conclusion. Lymph node TB was more common in women. Treatment outcomes were similar in both sexes, but women had a lower mortality rate.
Filiaciones:
:
Gambo Rural Gen Hosp, Dept Med & Pediat, Oromiya, Ethiopia
Alicante Gen Univ Hosp, ISABIAL, Dept Internal Med, Alicante, Spain
Miguel Hernandez Univ Elche, Alicante, Spain
Comeche, B:
Gambo Rural Gen Hosp, Dept Med & Pediat, Oromiya, Ethiopia
Ramon y Cajal Univ Hosp, IRICYS, Natl Referral Unit Trop Dis, Infect Dis Dept, Madrid, Spain
Tesfamariam, A:
Gambo Rural Gen Hosp, Dept Med & Pediat, Oromiya, Ethiopia
Reyes, F:
Gambo Rural Gen Hosp, Dept Med & Pediat, Oromiya, Ethiopia
Tiziano, G:
Gambo Rural Gen Hosp, Dept Med & Pediat, Oromiya, Ethiopia
Balcha, S:
Gambo Rural Gen Hosp, Dept Med & Pediat, Oromiya, Ethiopia
Edada, T:
Gambo Rural Gen Hosp, Dept Med & Pediat, Oromiya, Ethiopia
Biru, D:
Gambo Rural Gen Hosp, Dept Med & Pediat, Oromiya, Ethiopia
Perez-Butragueno, M:
Gambo Rural Gen Hosp, Dept Med & Pediat, Oromiya, Ethiopia
Infanta Leonor Univ Hosp, Dept Pediat, Madrid, Spain
Gorgolas, M:
Gambo Rural Gen Hosp, Dept Med & Pediat, Oromiya, Ethiopia
Fdn Jimenez Diaz, Univ Hosp, Div Infect Dis, Madrid, Spain
Auton Univ Madrid, Madrid, Spain
Green Published, Hybrid Gold
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