Antioxidant Supplementation Modulates Neutrophil Inflammatory Response to Exercise-Induced Stress.
Por:
Carrera-Quintanar L, Funes L, Herranz-López M, Martínez-Peinado P, Pascual-García S, Sempere JM, Boix-Castejón M, Córdova A, Pons A, Micol V and Roche E
Publicada:
7 dic 2020
Ahead of Print:
7 dic 2020
Resumen:
The aim of the present report was to evaluate the inflammatory response to a 2000-m running test considering neutrophil myeloperoxidase as an inflammatory marker, and to verify if supplements rich in antioxidants could modulate Post-test antioxidant and anti-inflammatory responses. To this end, a 21-day homogenization period was carried out with three groups: a control group, a supplemented group taking an almond beverage enriched with vitamins C and E and a third group consuming the same beverage but enriched with Lippia citriodora extract. At the end of this period, participants performed a 2000-m run, and blood samples were obtained the day before and immediately after the running test. Plasma and neutrophils were isolated. As a result, plasma creatine kinase and myoglobin increased, indicating Post-test muscle damage. Plasma oxidative markers were increased in all groups, except in the group supplemented with the almond beverage. Neutrophil antioxidant enzymes were significantly increased only in the control group, suggesting an antioxidant effect of the supplements provided in the other groups. Myeloperoxidase activity was significantly increased after the test in the control group, while increased enzyme levels were detected in plasma of the supplement groups. Therefore, antioxidant consumption seems to favour myeloperoxidase release. The connection of this observation with post-exercise recovery will require further investigation.
Filiaciones:
Carrera-Quintanar L:
Food Science Laboratory, Department of Human Reproduction, Growth and Child Development, University of Guadalajara, Guadalajara 44340, Mexico
Funes L:
Institute of Research, Development and Innovation in Healthcare Biotechnology of Elche (IDiBE), Miguel Hernández University (UMH), Elche, 03202 Alicante, Spain
Herranz-López M:
Institute of Research, Development and Innovation in Healthcare Biotechnology of Elche (IDiBE), Miguel Hernández University (UMH), Elche, 03202 Alicante, Spain
:
Department of Biotechnology, University of Alicante, 03690 Alicante, Spain
:
Department of Biotechnology, University of Alicante, 03690 Alicante, Spain
:
Department of Biotechnology, University of Alicante, 03690 Alicante, Spain
:
Institute of Research, Development and Innovation in Healthcare Biotechnology of Elche (IDiBE), Miguel Hernández University (UMH), Elche, 03202 Alicante, Spain
Córdova A:
Department of Biochemistry and Physiology, Faculty of Health Sciences, Soria Campus, University of Valladolid, 42001 Soria, Spain
Pons A:
Research Group on Community Nutrition and Oxidative Stress, University of Balearic Islands, 07122 Palma de Mallorca, Balearic Islands, Spain
CIBER Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III (ISCIII), 28029 Madrid, Spain
:
Institute of Research, Development and Innovation in Healthcare Biotechnology of Elche (IDiBE), Miguel Hernández University (UMH), Elche, 03202 Alicante, Spain
CIBER Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III (ISCIII), 28029 Madrid, Spain
:
CIBER Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III (ISCIII), 28029 Madrid, Spain
Department of Applied Biology-Nutrition and Institute of Bioengineering, Alicante Institute for Health and Biomedical Research (ISABIAL), Miguel Hernández University (UMH), 03010 Alicante, Spain
Gold, Green Published
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