Urate levels and clearance in renal patients under peritoneal dialysis
Por:
Diez-Lopez, C, Perez-Contreras, J and Andres, M
Publicada:
1 jun 2021
Ahead of Print:
1 may 2021
Resumen:
Hemodialysis adequately controls serum uric acid (UA) levels, making UA-lowering drugs unnecessary; scant data are available for peritoneal dialysis (PD). We analyzed blood, 24 h urine and dialysis fluid from twenty patients under PD, to assess UA levels and clearances, and factors associated with better performance and maintenance of target levels (<6mg/dL). Median serum UA was 5.4 mg/dL (p25-75 4.4-5.8), mainly achieved through peritoneal clearance (3.0 mL/min/1.73m(2), 71.2% of total UA clearance); 75% of participants was on UA targets. Continuous cycling peritoneal dialysis showed highest UA clearance and target achievements. These findings may be of interest for end-stage renal patients with gout.
Filiaciones:
Diez-Lopez, C:
Gen Univ Hosp Alicante ISABIAL, Nephrol Serv, Alicante, Spain
:
Gen Univ Hosp Alicante ISABIAL, Nephrol Serv, Alicante, Spain
Univ Miguel Hernandez, Dept Clin Med, Alicante, Spain
:
Univ Miguel Hernandez, Dept Clin Med, Alicante, Spain
Gen Univ Hosp Alicante ISABIAL, Rheumatol Sect, Alicante, Spain
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