Effectiveness of a Multicomponent Group Psychological Intervention Program in Patients with Inflammatory Bowel Disease: A Randomized Trial
Por:
Bernabeu, P, van-der Hofstadt, C, Rodriguez-Marin, J, Gutierrez, A, Alonso, M, Zapater, P, Jover, R and Sempere, L
Publicada:
1 may 2021
Ahead of Print:
19 may 2021
Resumen:
(1) Background: Stress, anxiety, and depression have been identified as factors that influence the development of inflammatory bowel disease (IBD). The main aim of this study was to test the effectiveness of group multicomponent cognitive-behavioral therapy at reducing stress, anxiety, and depression, and improving quality of life and the clinical course of the disease. (2) Methods: A total of 120 patients were evaluated using the General Perceived Stress Scale, Scale of Stress Perceived by the Disease, the anxiety and depression scale, and quality of life questionnaire for patients with IBD. Disease activity was measured using the Mayo Index for ulcerative colitis and CDAI for Crohn's disease, as well as the number of relapses self-reported by patients. Patients were randomized to receive group multicomponent cognitive-behavioral therapy or treatment as usual. (3) Results: The psychological intervention reduced stress (EAE: 45.7 +/- 8.8 vs. 40.6 +/- 8.4, p = 0.0001; PSS: 28.0 +/- 7.3 vs. 25.1 +/- 5.9, p = 0.001) and improved quality of life (164.2 +/- 34.3 vs. 176.2 +/- 28.0, p = 0.001). An improvement was found in the number of relapses self-reported by patients (0.2 relapses/patient vs. control 0.7 relapses/patient; p = 0.027). No differences were found in disease activity indexes. (4) Conclusions: Psychological therapy was associated with improved stress, quality of life and with a decrease in the number of relapses self-reported by patients. Clinical trial registration number: NCT02614014.
Filiaciones:
:
Hosp Gen Univ Alicante, Inst Invest Sanit ISABIAL, Hlth Psychol Dept, Alicante 03010, Spain
:
Hosp Gen Univ Alicante, Inst Invest Sanit ISABIAL, Hlth Psychol Dept, Alicante 03010, Spain
Rodriguez-Marin, J:
Univ Miguel Hernandez, Dept Psicol Salud, Elche 03202, Spain
:
Hosp Gen Univ Alicante, Inst Invest Sanit ISABIAL, Serv Med Digest, Alicante 03010, Spain
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Hosp Gen Univ Alicante, Inst Invest Sanit ISABIAL, Hlth Psychol Dept, Alicante 03010, Spain
:
Hosp Gen Univ Alicante, Inst Invest Sanit ISABIAL, Clin Pharmachol Dept, Alicante 03010, Spain
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Hosp Gen Univ Alicante, Inst Invest Sanit ISABIAL, Serv Med Digest, Alicante 03010, Spain
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Hosp Gen Univ Alicante, Inst Invest Sanit ISABIAL, Serv Med Digest, Alicante 03010, Spain
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