National consensus on the cardiological treatment and follow-up of Kawasaki disease
Por:
Sombrero, H, Fernandez-Cooke, E, Sanchez-Manubens, J, Picarzo, J, de la Torre, L, Alvarez-Fuente, M, Garcia, G, Gutierrez-Larraya, F, Vazquez, B, McMullan, P, Perez, G, Arboledas, F, Martin, C, Echauri, J, Garcia, P, Arevalo, P, Rofes, A, Sanchez, M, Domingo, E, Rodrigo, A, Abbona, M, Fernandez, I, Tascon, A, Torralva, C, Jover, E, Rodriguez, C, Trigo, S, Sayago, M, Diaz, M, Tejedor, M, Moreno, J, Blesa, C, Bellon, J, Cassanello, M, Malfaz, F, Spoturno, A, Hernandez, R, Orvay, J, Marcos, D, Manotas, H, Peiro, V, de Caro, A, Cancho, M, Iglesias, L, Bronte, L, Menendez, B, Megias, L, Tomas, J, Colina, P, Garcia, O, Garrido, M, Manzano, P, Bedoya, J, Espinosa, J, Nava, F, Pinela, H, Asenjo, M, Ruiz, A, Aracama, J, Sarabia, J, Soria, M, Suarez, N, Belda, A, Villar, S, Garcia, J, Moure, A, de Vinuesa, A, Arzoz, M, Angleu, F, Cerro, E, Rodriguez-Monte, M, Villanueva, N, Crespo, M, Garcia, G, Carrasco, M, Marin, M, Menchen, C, Ipina, F, Rodriguez, I, Esteve, M, Gomez, M, Blanco, A, Sanchez, Y, del Rey, C, Fernandez, A, Martin, G, Fos, I, Riezu, M, Casso, M, Montanes, L, de Lera, C, Navarro, L, Abel, B, Balseiro, M, Gonzalez, J, Julian, N, Cazcarra, J, Toral, M, Linero, A, Garcia, B, Llagaria, M, Alonso, S, Blanch, C, de Lara, I, del Villar, M, Lorente, M, Oloron, P, Soto, M, Checa, L, Morillo, M, Lopez, C, Abad, P, Ortiz, F, Gutierrez, A, Tirado, A, Montes, A, Matamala, A, Garrido, A, Erroz, I, Argueta, J, Aguera, L, Molina, E, Salas, J, Carrillo, C, Campos, D, Herrera, V, Agapito, M, Munuzuri, A, Pardo, A, Roldan, J, Picarzo, F, Moreno, M, Perin, F, Fuentes, I, Izquierdo, B, Morales, M, Dalmau, M, Ovalle, E, Poveda, M, Rodriguez, S, Garcia, S, Arcelus, E, Mendez, B, Armada, A, Jimenez, N, Gonzalez, M, Mesa, M, Serrano, R, Sombrero, M, Barba, V, Ibarra, C, Vivas, F, Nunez, F, Soriano, J, Rotes, A, Salguero, F, Capunay, J, Peracaula, C, Andres, A, Calderon, A, Vaquerizo, C, Pascual, E, Robles, M, Sanchez-Manjavacas, A, Baladron, A, Garcia, R, Belmonte, D, Garcia, M, Cabrera, P, Moreno, A, Moreno, R, Hernandez, M, Rico, M, Prat, S, Carrasco, A, Padrino, E, Adan, M, Albert, S, Nogales, J, Walter, C, Martin, M, Casajona, M and SECPCC
Publicada:
1 sep 2018
Categoría:
Pediatrics, perinatology and child health
Resumen:
Kawasaki disease is a self-limiting acute vasculitis that affects small and medium-sized vessels, and is the most common cause of acquired heart disease in children in our environment. Up to 25% of untreated patients develop coronary aneurysms. It is suspected that an infectious agent may be the trigger of the disease, but the causative agent is still unknown. Based on the previous evidence, recommendations are proposed for the diagnosis, treatment of acute disease, and the long-term management of these patients, in order to unify criteria. The diagnosis must be quick, based on easy-to-use algorithms and with the support of complementary tests. This document includes the indication of available imaging techniques, as well as the planning of cardiological examinations based on the initial involvement. Intravenous immunoglobulin is the basis of the initial treatment. The role of corticosteroids is still controversial, but there are studies that support its use as adjuvant treatment. A multidisciplinary working group has developed a scheme with different treatment guidelines depending on the risk factors at diagnosis, the patient's clinical situation, and response to previous treatment, including indications for thromboprophylaxis in patients with coronary involvement. The stratification of risk for long-term treatment is essential, as well as the recommendations on the procedures based on the initial cardiological involvement and its progression. Patients with coronary aneurysms require continuous and uninterrupted cardiological monitoring for life. (C) 2018 Asociacion Espanola de Pediatria. Published by Elsevier Espana, S.L.U.
Filiaciones:
Sombrero, H:
Soc Espanola Cardiol Pediat & Cardiopatias Congen, Madrid, Spain
Hosp Univ Principe Asturias, Serv Pediat, Cardiol Infantil, Madrid, Spain
Fernandez-Cooke, E:
Hosp Materno Infantil Doce Octubre, Serv Pediat, Unidad Enfermedades Infecciosas, Madrid, Spain
Soc Espanola Infectol Pediat, Madrid, Spain
Sanchez-Manubens, J:
Hosp Parc Tauli, Serv Pediat, Unidad Reumatol Pediat, Barcelona, Spain
Soc Espanola Reumatol Pediat, Madrid, Spain
Picarzo, J:
Soc Espanola Cardiol Pediat & Cardiopatias Congen, Madrid, Spain
Hosp Univ Fdn Alcorcon, Serv Pediat, Cardiol Infantil, Madrid, Spain
de la Torre, L:
Hosp Materno Infantil Doce Octubre, Madrid, Spain
Alvarez-Fuente, M:
Hosp Ramon & Cajal, Madrid, Spain
Garcia, G:
Hosp Materno Infantil Vall dHebron, Barcelona, Spain
Soc Espanola Cardiol, Madrid, Spain
Gutierrez-Larraya, F:
Soc Espanola Cardiol, Madrid, Spain
Hosp Univ La Paz, Madrid, Spain
Vazquez, B:
Hosp Materno Infantil Doce Octubre, Madrid, Spain
Soc Espanola Cardiol, Madrid, Spain
McMullan, P:
Hosp Univ Fdn Alcorcon, Madrid, Spain
Perez, G:
Hosp Nens Barcelona, Barcelona, Spain
Arboledas, F:
Complejo Hosp Jaen, Jaen, Spain
Martin, C:
Hosp Univ Rio Hortega, Valladolid, Spain
Echauri, J:
Hosp Univ Marques de Valdecilla, Santander, Cantabria, Spain
Garcia, P:
Hosp Son LLatzer, Palma De Mallorca, Mallorca, Spain
Arevalo, P:
Hosp San Francisco de Asis, Madrid, Spain
Sanchez, M:
Hosp Severo Ochoa, Madrid, Spain
Domingo, E:
Hosp La Paz, Madrid, Spain
Rodrigo, A:
Hosp Univ Nino Jesus, Madrid, Spain
Abbona, M:
Hosp Univ Mutua Terrassa, Barcelona, Spain
Fernandez, I:
Hosp Univ Principe Asturias, Madrid, Spain
Tascon, A:
Hosp Univ Infanta Sofia, Serv Pediat, Cardiol Infantil, Madrid, Spain
Soc Espanola Cardiol Pediat & Cardiopatias Congen, Madrid, Spain
Hosp Univ Infanta Sofia, Madrid, Spain
Torralva, C:
Hosp Perpetuo Socorro, Las Palmas Gran Canaria, Las Palmas, Spain
Jover, E:
Hosp Clin San Carlos, Madrid, Spain
Rodriguez, C:
Ctr Salud Infanta Mercedes, Madrid, Spain
Trigo, S:
Hosp Univ Cruces, Baracaldo, Vizcaya, Spain
Sayago, M:
Hosp Costa del Sol, Malaga, Spain
Diaz, M:
Hosp Infanta Elena, Madrid, Spain
Tejedor, M:
Hosp Rio Carrion, Palencia, Spain
Moreno, J:
Hosp Univ La Fe, Valencia, Spain
Politecn La Fe, Valencia, Spain
Blesa, C:
Hosp Univ Virgen de las Nieves, Granada, Spain
Bellon, J:
Hosp St Joan de Deu, Barcelona, Spain
Cassanello, M:
Hosp Univ Gen Catalunya, Barcelona, Spain
Malfaz, F:
Soc Espanola Cardiol Pediat & Cardiopatias Congen, Madrid, Spain
Hosp Univ Rio Hortega, Serv Pediat, Cardiol Infantil, Valladolid, Spain
Hosp Univ Rio Hortega, Valladolid, Spain
Spoturno, A:
Ctr Med Mediterraneo, Almeria, Spain
Hernandez, R:
Hosp Univ St Joan, Tarragona, Spain
Orvay, J:
Hosp Can Misses, Ibiza, Spain
Marcos, D:
Hosp Univ Fdn Alcorcon, Madrid, Spain
Manotas, H:
Hosp Ciudad Coria, Caceres, Spain
Peiro, V:
Hosp Univ Carlos Haya, Malaga, Spain
de Caro, A:
Hosp Vega, Murcia, Spain
Cancho, M:
Hosp Gen Villalba, Madrid, Spain
Iglesias, L:
Hosp Valle De Hebron, Barcelona, Spain
Bronte, L:
Hosp Univ La Paz, Madrid, Spain
Menendez, B:
Hosp Univ 12 Octubre, Madrid, Spain
Megias, L:
Complejo Hosp Univ Albacete, Albacete, Spain
Tomas, J:
Ctr Med Asturias, Oviedo, Spain
Colina, P:
Hosp Valle De Hebron, Barcelona, Spain
Garcia, O:
Hosp Virgen de la Salud, Toledo, Spain
Garrido, M:
Fdn Jimenez Diaz, Madrid, Spain
Manzano, P:
Hosp Univ 12 Octubre, Madrid, Spain
Bedoya, J:
Hosp Don Benito Villa Nueva, Badajoz, Spain
Espinosa, J:
Hosp Gen Univ Gregorio Maranon, Madrid, Spain
Nava, F:
Hosp Virgen de la Pena, Fuerteventura, Las Palmas, Spain
Pinela, H:
Hosp Univ Torrejon, Madrid, Spain
Asenjo, M:
Hosp Univ Ramon y Cajal, Madrid, Spain
Ruiz, A:
Hosp Univ Nuestra Senora Candelaria, Santa Cruz De Tenerife, Spain
Aracama, J:
Hosp Univ Cent Asturias, Oviedo, Asturias, Spain
Sarabia, J:
Hosp Univ Canarias, San Cristobal la Laguna, Santa Cruz De T, Spain
Soria, M:
Hosp Univ Infanta Cristina, Madrid, Spain
Suarez, N:
Hosp Univ Cruces, Baracaldo, Vizcaya, Spain
Belda, A:
Hosp Vinalopo, Alicante, Spain
Villar, S:
Hosp Univ Mutua Terrassa, Barcelona, Spain
Garcia, J:
Complejo Hosp Univ Ourense, Orense, Spain
Moure, A:
Hosp Maternoinfantil Teresa Herrera, La Coruna, Spain
de Vinuesa, A:
Hosp Univ Virgen Macarena, Seville, Spain
Arzoz, M:
Hosp Sureste, Madrid, Spain
Angleu, F:
Hosp Infantil Virgen del Rocio, Seville, Spain
Cerro, E:
Hosp Univ Principe Asturias, Madrid, Spain
Rodriguez-Monte, M:
Hosp Univ Ramon y Cajal, Madrid, Spain
Villanueva, N:
Hosp Univ Infanta Leonor, Madrid, Spain
Crespo, M:
Hosp Univ La Fe, Valencia, Spain
Politecn La Fe, Valencia, Spain
Garcia, G:
Hosp Valle De Hebron, Barcelona, Spain
Carrasco, M:
Hosp Univ Severo Ochoa, Madrid, Spain
Marin, M:
Hosp Gen Ciudad Real, Ciudad Real, Spain
Menchen, C:
Hosp Clin San Carlos, Madrid, Spain
Ipina, F:
Hosp Univ Vall dHebron, Barcelona, Spain
Rodriguez, I:
Hosp Virgen de Valme, Seville, Spain
Esteve, M:
Hosp Univ La Fe, Valencia, Spain
Politecn La Fe, Valencia, Spain
Gomez, M:
Hosp Univ Virgen Macarena, Seville, Spain
Blanco, A:
Hosp Int Medimar, Alicante, Spain
Sanchez, Y:
Hosp Marina Baixa, Alicante, Spain
del Rey, C:
Hosp Univ Virgen del Rocio, Seville, Spain
Fernandez, A:
Hosp Univ Cent Asturias, Oviedo, Asturias, Spain
Martin, G:
Hosp Virgen de la Salud, Toledo, Spain
Fos, I:
Hosp Gen Univ Elche, Alicante, Spain
Riezu, M:
Hosp Univ Donostia, San Sebastian, Spain
Casso, M:
Hosp Gen Segovia, Segovia, Spain
Montanes, L:
Hosp Miguel Servet, Zaragoza, Spain
de Lera, C:
Hosp Univ La Paz, Madrid, Spain
Navarro, L:
Hosp Univ Infanta Sofia, Madrid, Spain
Abel, B:
Hosp Clin Univ, La Coruna, Spain
Balseiro, M:
Hosp Maternoinfantil Teresa Herrera, La Coruna, Spain
Gonzalez, J:
Hosp Marcide Novoa Santos, Ferrol, A Coruna, Spain
Julian, N:
Hosp UPS Marbella, Malaga, Spain
Cazcarra, J:
Hosp Terrassa, Barcelona, Spain
Toral, M:
Hosp Gen Villalba, Madrid, Spain
Linero, A:
Hosp Univ Vall dHebron, Barcelona, Spain
Garcia, B:
Hosp Univ Vall dHebron, Barcelona, Spain
Llagaria, M:
Hosp Gen Valencia, Valencia, Spain
Alonso, S:
Hosp Maternoinfantil Teresa Herrera, La Coruna, Spain
Blanch, C:
Hosp Univ St Joan, Tarragona, Spain
:
Hosp Gen Univ Alicante, Alicante, Spain
del Villar, M:
Hosp Gen Univ Alicante, Alicante, Spain
Lorente, M:
Hosp Rafael Mendez, Murcia, Spain
Oloron, P:
Hosp Virgen del Camino, Pamplona, Navarra, Spain
Soto, M:
Complejo Hosp Univ Santiago, La Coruna, Spain
Checa, L:
Clin Valles, Barcelona, Spain
Morillo, M:
Hosp Gen Mancha Ctr, Ciudad Real, Spain
Lopez, C:
Hosp Univ Gregorio Maranon, Madrid, Spain
Abad, P:
Hosp Univ Virgen del Rocio, Seville, Spain
Ortiz, F:
Hosp Nuestra Senora Prado, Toledo, Spain
Gutierrez, A:
Hosp Lluis Alcanyis, Valencia, Spain
Tirado, A:
Hosp Univ Virgen del Rocio, Seville, Spain
Montes, A:
Complejo Hosp Torrecardenas, Almeria, Spain
Matamala, A:
Hosp Univ Guadalajara, Guadalajara, Spain
Garrido, A:
Royal Brompton Hosp, London, England
Erroz, I:
Complejo Asistencial Univ Leon, Leon, Spain
Argueta, J:
Corp Sanitaria Parc Tauli, Barcelona, Spain
Aguera, L:
CS Babel, IMED Elche, Alicante, Spain
Molina, E:
Hosp Univ La Fe, Valencia, Spain
Politecn La Fe, Valencia, Spain
Salas, J:
Hosp Tajo, Madrid, Spain
Carrillo, C:
Hosp Univ Canarias, San Cristobal la Laguna, Santa Cruz De T, Spain
Campos, D:
Hosp Univ Fuenlabrada, Madrid, Spain
Herrera, V:
Hosp Mataro, Consorci Sanitari Maresme, Barcelona, Spain
Agapito, M:
Hosp Univ La Paz, Madrid, Spain
Munuzuri, A:
Hosp Clin Univ, La Coruna, Spain
Pardo, A:
Hosp Gen Cataluna, Barcelona, Spain
Roldan, J:
Hosp Univ Cruces, Baracaldo, Vizcaya, Spain
Picarzo, F:
Hosp Univ Fdn Alcorcon, Madrid, Spain
Moreno, M:
HM Univ Monteprincipe, Madrid, Spain
Perin, F:
Hosp Univ Virgen de las Nieves, Granada, Spain
Fuentes, I:
Hosp Univ Severo Ochoa, Madrid, Spain
Izquierdo, B:
Hosp Univ Salamanca, Salamanca, Spain
Morales, M:
Hosp Plana, Villareal, Castellon, Spain
Dalmau, M:
Hosp Univ Doctor Josep Trueta, Girona, Spain
Ovalle, E:
Hosp Univ Infanta Elena, Madrid, Spain
Poveda, M:
Hosp Univ Infanta Sofia, Madrid, Spain
Rodriguez, S:
Hosp Clin Univ Valladolid, Valladolid, Spain
Garcia, S:
Complejo Hosp Univ Ourense, Orense, Spain
Arcelus, E:
Hosp Univ Donostia, San Sebastian, Spain
Mendez, B:
Hosp Univ San Pedro, Logrono, La Rioja, Spain
Armada, A:
NE22HS, Newcastle Upon Tyne, Tyne & Wear, England
Jimenez, N:
Hosp Univ Ramon y Cajal, Madrid, Spain
Gonzalez, M:
Hosp Univ Puerta del Mar, Cadiz, Spain
Mesa, M:
Hosp Univ Infanta Cristina, Madrid, Spain
Serrano, R:
Hosp Univ Basurto, Bilbao, Vizcaya, Spain
Sombrero, M:
Hosp Univ Principe Asturias, Madrid, Spain
Barba, V:
Hosp Gen Ciudad Real, Ciudad Real, Spain
Ibarra, C:
Hosp Virgen del Camino, Pamplona, Navarra, Spain
Vivas, F:
Hosp Univ Maternoinfantil, Badajoz, Spain
Nunez, F:
Hosp Maternoinfantil Teresa Herrera, La Coruna, Spain
Soriano, J:
Hosp Univ La Fe, Valencia, Spain
Rotes, A:
Hosp Univ Vall dHebron, Barcelona, Spain
Salguero, F:
Hosp SAS Jerez, Cadiz, Spain
Capunay, J:
Hosp Seguro Social Peru, Trujillo, Peru
Peracaula, C:
Hosp SAS Jerez, Cadiz, Spain
Andres, A:
Soc Espanola Cardiol, Madrid, Spain
Calderon, A:
Hosp Henares, Madrid, Spain
Vaquerizo, C:
Hosp Univ 12 Octubre, Madrid, Spain
Pascual, E:
Hosp Univ La Paz, Madrid, Spain
Robles, M:
Hosp Gen Elche, Alicante, Spain
Sanchez-Manjavacas, A:
Hosp Univ Puerta de Hierro, Madrid, Spain
Baladron, A:
Hosp Gen Univ Gregorio Maranon, Madrid, Spain
Garcia, R:
Hosp Univ Infanta Leonor, Madrid, Spain
Belmonte, D:
Hosp Univ Mutua Terrassa, Barcelona, Spain
Garcia, M:
Hosp Gen Univ Santa Lucia, Murcia, Spain
Cabrera, P:
Hosp Univ Maternoinfantil Canarias, Las Palmas Gran Canaria, Las Palmas, Spain
Moreno, A:
Hosp Univ Nino Jesus, Madrid, Spain
Moreno, R:
Hosp Univ Ramon y Cajal, Madrid, Spain
Hernandez, M:
Hosp Univ Reina Sofia, Cordoba, Spain
Rico, M:
Hosp Punta de Europa, Cadiz, Spain
Prat, S:
Hosp Univ Doctor Josep Trueta, Girona, Spain
Carrasco, A:
Hosp Univ Puerta de Hierro, Madrid, Spain
Padrino, E:
Hosp Univ Severo Ochoa, Madrid, Spain
Adan, M:
Hosp Obispo Polanco, Teruel, Spain
Albert, S:
Hosp Univ Monteprincipe, Unidad Cardiopatias Congenitas, Madrid, Spain
Nogales, J:
Ctr Salud Guadarrama, Madrid, Spain
Walter, C:
Hosp St Joan de Deu, Barcelona, Spain
Martin, M:
Hosp Univ 12 Octubre, Madrid, Spain
Casajona, M:
Hosp St Joan de Deu, Barcelona, Spain
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