Chronic hand eczema: clinical characterization, aetiology, concomitant foot eczema and polysensitization
Por:
Lopez-Castillo, D, Descalzo, M, Olmos-Alpiste, F, Hita, J, Redondo, V, Gavin, J, Gonzalez, I, Garcia, P, Perez, J, Silvestre, J and Gimenez-Arnau, A
Publicada:
1 ene 2022
Resumen:
Background Chronic hand eczema (CHE) is a disabling dermatosis that presents with concomitant conditions, such as foot eczema and contact sensitization Objectives To identify the characteristics of the CHE population, with particular emphasis on occupational relevance and evaluation of concomitant foot eczema and polysensitization Materials & Methods A total of 2,926 patch-tested patients, presenting with CHE from different specialized dermatological units from 2004 to 2014, were evaluated. A global descriptive characterization was performed including hand subtype analysis, as well as accurate evaluation of polysensitization Results The most frequent global CHE diagnostic was irritant contact dermatitis (42%) and, for patients with foot and chronic hand eczema (FCHE), allergic contact dermatitis (28%). Of CHE cases, 39% showed occupational relevance. Positivity to at least one allergen was found in 55% of patients, with nickel and methylisothiazolinone (MI) being the most prevalent. Methylchloroisothiazolinone/MI, nickel and potassium dichromate showed the highest occupational relevance. Patients with concomitant FCHE (8%) showed greater sensitization for potassium dichromate and cobalt chloride. Twelve percent were polysensitized, with MI being the most frequently involved contact allergen Conclusion Patch testing for FCHE and CHE revealed a specific contact allergen and occupational profile. MI was the most frequently reported allergen related to polysensitization in CHE
Filiaciones:
Lopez-Castillo, D:
Univ Autonoma Barcelona, Hosp Mar, Dept Dermatol, IMIM, Barcelona, Spain
Descalzo, M:
Spanish Acad Dermatol & Venereol, Fdn Piel Sana, Madrid, Spain
Olmos-Alpiste, F:
Univ Autonoma Barcelona, Hosp Mar, Dept Dermatol, IMIM, Barcelona, Spain
Hita, J:
Puerto Real Univ Hosp, Dept Dermatol, Cadiz, Spain
Redondo, V:
Univ Hosp Santiago, Dept Dermatol, Santiago De Compostela, Spain
Gavin, J:
Univ Hosp Complex Xeral Cies, Dept Dermatol, Vigo, Spain
Gonzalez, I:
Univ Care Complex Leon CAULE, Dept Dermatol, Leon, Spain
Garcia, P:
Univ Gen Hosp Morales Meseguer, Dept Dermatol, Murcia, Spain
Perez, J:
Univ Hosp Princesa, Dept Dermatol, Madrid, Spain
:
Univ Gen Hosp Alicante, Dept Dermatol, Alicante, Spain
Gimenez-Arnau, A:
Univ Autonoma Barcelona, Hosp Mar, Dept Dermatol, IMIM, Barcelona, Spain
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